Journal: Frontiers in Oncology

Article Title: Feasibility of Optical Surface-Guidance for Position Verification and Monitoring of Stereotactic Body Radiotherapy in Deep-Inspiration Breath-Hold

doi: 10.3389/fonc.2020.573279

Figure Lengend Snippet: (A) Work flow of patient set-up and localization until treatment delivery together with (B) an example screenshot of one of our SBRT patients showing a typical region of interest (ROI) placed to the lower thorax for DIBH monitoring of a liver target.

Article Snippet: For monitoring of correct DIBH reproducibility the hard- and software tools of Vision RT Ltd. (London, United Kingdom) were used.

Techniques:

Journal: Frontiers in Oncology

Article Title: Feasibility of Optical Surface-Guidance for Position Verification and Monitoring of Stereotactic Body Radiotherapy in Deep-Inspiration Breath-Hold

doi: 10.3389/fonc.2020.573279

Figure Lengend Snippet: Box plots with boxes extending from 25th to 75th percentiles. Whiskers are drawn down to 5th and up to 95th percentiles, respectively. (A) Couch shifts are shown in left (+) to right (–), cranial (+) to caudal (–) and anterior (+) to posterior (–) directions along the x -, y -, and z -axis, respectively. Values were grouped by target location and derived from first CBCTs for position verification after alignment of current DIBH surface to that of the reference surface. (B) Length of correction vectors of first CBCTs for image-guidance in DIBH and grouped by target location. Statistical difference was calculated by Welch’s t -test.

Article Snippet: For monitoring of correct DIBH reproducibility the hard- and software tools of Vision RT Ltd. (London, United Kingdom) were used.

Techniques: Derivative Assay

Journal: Frontiers in Oncology

Article Title: Feasibility of Optical Surface-Guidance for Position Verification and Monitoring of Stereotactic Body Radiotherapy in Deep-Inspiration Breath-Hold

doi: 10.3389/fonc.2020.573279

Figure Lengend Snippet: Volumes of gross tumor (GTV), clinical target volume (CTV), internal target volume (ITV) and planning target in DIBH (CTV DIBH and PTV DIBH) as well as in free-breathing (ITV FB and PTV FB) for (A) all patients and (B) grouped by target location. Statistical differences were calculated by paired t -test.

Article Snippet: For monitoring of correct DIBH reproducibility the hard- and software tools of Vision RT Ltd. (London, United Kingdom) were used.

Techniques:

Journal: Cancers

Article Title: Interaction between Radiation Therapy and Targeted Therapies in HER2-Positive Breast Cancer: Literature Review, Levels of Evidence for Safety and Recommendations for Optimal Treatment Sequence

doi: 10.3390/cancers15082278

Figure Lengend Snippet: Guidelines, precautions, and advice for humanized monoclonal antibody (MAB) targeting HER2.

Article Snippet: Pertuzumab , 18 , Yes , ESMO: “It is recommended to decide on the administration of 1 year of trastuzumab/ Pertuzumab based on the risk assessment at diagnosis; the treatment may start before or after the surgery, in accordance with the approval wording by the regulators”. , Cautious in case of abdomen and pelvic irradiation that includes large GI volume , AVMI/tomotherapy DIBH [ ]. No data on fractionation. .

Techniques: Adjuvant, Irradiation, Biomarker Discovery